Lopinavir/Ritonavir Pharmacokinetics in HIV/HCV-Coinfected Patients With or Without Cirrhosis

Liver disease may alter the pharmacokinetics of antiretrovirals and produce changes in plasma protein binding. The aim was to evaluate the pharmacokinetics of total and unbound lopinavir (LPV) in HIV-infected patients with and without hepatitis C virus (HCV) coinfection. Fifty-six HIV+ patients rece...

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Detalhes bibliográficos
Principais autores: Micheli, Valeria, Regazzi, Mario, Dickinson, Laura, Meraviglia, Paola, Villani, Paola, Khoo, Saye H., Viganò, Paolo, Cordier, Laura, Cusato, Maria, Duca, Piergiorgio, Orlando, Giovanna, Rizzardini, Giuliano, Back, David J., Cargnel, Antonietta
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672992/
https://ncbi.nlm.nih.gov/pubmed/18520602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e318177209e
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