Lopinavir/Ritonavir Pharmacokinetics in HIV/HCV-Coinfected Patients With or Without Cirrhosis

Liver disease may alter the pharmacokinetics of antiretrovirals and produce changes in plasma protein binding. The aim was to evaluate the pharmacokinetics of total and unbound lopinavir (LPV) in HIV-infected patients with and without hepatitis C virus (HCV) coinfection. Fifty-six HIV+ patients rece...

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Bibliografische gegevens
Hoofdauteurs: Micheli, Valeria, Regazzi, Mario, Dickinson, Laura, Meraviglia, Paola, Villani, Paola, Khoo, Saye H., Viganò, Paolo, Cordier, Laura, Cusato, Maria, Duca, Piergiorgio, Orlando, Giovanna, Rizzardini, Giuliano, Back, David J., Cargnel, Antonietta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672992/
https://ncbi.nlm.nih.gov/pubmed/18520602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e318177209e
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