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Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection

Vascular endothelium is vulnerable to the attack of glucose-derived oxoaldehydes (glyoxal and methylglyoxal) during diabetes, through the formation of advanced glycation end products (AGEs). Although aminoguanidine (AG) has been shown to protect against the AGE-induced adverse effects, its protectio...

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書誌詳細
主要な著者: Sliman, Sean M., Eubank, Timothy D., Kotha, Sainath R., Kuppusamy, M. Lakshmi, Sherwani, Shariq I., O’Connor Butler, Elizabeth Susan, Kuppusamy, Periannan, Roy, Sashwati, Marsh, Clay B., Stern, David M., Parinandi, Narasimham L.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671881/
https://ncbi.nlm.nih.gov/pubmed/19585224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0199-x
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