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Nanomolar vitamin E α-tocotrienol inhibits glutamate-induced activation of phospholipase A(2) and causes neuroprotection

Our previous works have elucidated that the 12-lipoxygenase (12-Lox) pathway is directly implicated in glutamate-induced neural cell death, and that such that toxicity is prevented by nM concentrations of the natural vitamin E α-tocotrienol (TCT). In the current study we tested the hypothesis that p...

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Detalles Bibliográficos
Main Authors: Khanna, Savita, Parinandi, Narasimham L., Kotha, Sainath R., Roy, Sashwati, Rink, Cameron, Bibus, Douglas, Sen, Chandan K.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821814/
https://ncbi.nlm.nih.gov/pubmed/20028458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06550.x
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