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Instability and Chromatin Structure of Expanded Trinucleotide Repeats
Trinucleotide repeat expansion underlies at least 17 neurologic diseases. In affected individuals, the expanded locus is characterized by dramatic changes in chromatin structure and in repeat tract length. Interestingly, recent studies show that several chromatin modifiers, including a histone acety...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671858/ https://ncbi.nlm.nih.gov/pubmed/19540013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2009.04.007 |
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