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µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes
We present µLAS, a lab-on-chip system that concentrates, separates, and detects DNA fragments in a single module. µLAS speeds up DNA size analysis in minutes using femtomolar amounts of amplified DNA. Here we tested the relevance of µLAS for sizing expanded trinucleotide repeats, which cause over 20...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328573/ https://ncbi.nlm.nih.gov/pubmed/30631115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36632-5 |
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