µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes

We present µLAS, a lab-on-chip system that concentrates, separates, and detects DNA fragments in a single module. µLAS speeds up DNA size analysis in minutes using femtomolar amounts of amplified DNA. Here we tested the relevance of µLAS for sizing expanded trinucleotide repeats, which cause over 20...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Malbec, Rémi, Chami, Bayan, Aeschbach, Lorène, Ruiz Buendía, Gustavo A., Socol, Marius, Joseph, Pierre, Leïchlé, Thierry, Trofimenko, Evgeniya, Bancaud, Aurélien, Dion, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328573/
https://ncbi.nlm.nih.gov/pubmed/30631115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36632-5
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi