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Minimizing carry-over PCR contamination in expanded CAG/CTG repeat instability applications
Expanded CAG/CTG repeats underlie the aetiology of 14 neurological and neuromuscular disorders. The size of the repeat tract determines in large part the severity of these disorders with longer tracts causing more severe phenotypes. Expanded CAG/CTG repeats are also unstable in somatic tissues, whic...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5740160/ https://ncbi.nlm.nih.gov/pubmed/29269788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18168-2 |
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