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Mechanisms of trinucleotide repeat instability during human development

Trinucleotide expansion underlies several human diseases. Expansion occurs during multiple stages of human development in different cell types, and is sensitive to the gender of the parent who transmits the repeats. Repair and replication models for expansions have been described, but we do not know...

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Detalhes bibliográficos
Autor principal: McMurray, Cynthia T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175376/
https://ncbi.nlm.nih.gov/pubmed/20953213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2828
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