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Trinucleotide Repeat Instability: Genetic Features and Molecular Mechanisms

Trinucleotide repeat expansions are an important cause of inherited neurodegenerative disease. The expanded repeats are unstable, changing in size when transmitted from parents to offspring (inter‐generational instability, “meiotic instability”) and often showing size variation within the tissues of...

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Détails bibliographiques
Publié dans:Brain Pathol
Auteur principal: R. La Spada, Albert
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098141/
https://ncbi.nlm.nih.gov/pubmed/9217977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1997.tb00895.x
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