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Trinucleotide Repeat Instability: Genetic Features and Molecular Mechanisms

Trinucleotide repeat expansions are an important cause of inherited neurodegenerative disease. The expanded repeats are unstable, changing in size when transmitted from parents to offspring (inter‐generational instability, “meiotic instability”) and often showing size variation within the tissues of...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Autor principal: R. La Spada, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098141/
https://ncbi.nlm.nih.gov/pubmed/9217977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1997.tb00895.x
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