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Bidirectional transcription of trinucleotide repeats: roles for excision repair
Genomic instability at repetitive DNA regions in cells of the nervous system leads to a number of neurodegenerative and neuromuscular diseases, including those with an expanded trinucleotide repeat (TNR) tract at or nearby an expressed gene. Expansion causes disease when a particular base sequence i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720788/ https://ncbi.nlm.nih.gov/pubmed/23669397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.019 |
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