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Biochemical analysis of active site mutations of human polymerase η

DNA polymerase η (pol η) plays a critical role in suppressing mutations caused by the bypass of cis-syn cyclobutane pyrimidine dimers (CPD) that escape repair. There is evidence this is also the case for the oxidative lesion 7,8-dihydro-8-oxo-guanine (8-oxoG). Both of these lesions cause moderate to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Suarez, Samuel C., Beardslee, Renee A., Toffton, Shannon M., McCulloch, Scott D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669660/
https://ncbi.nlm.nih.gov/pubmed/23499771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2013.03.001
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