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Biochemical analysis of active site mutations of human polymerase η
DNA polymerase η (pol η) plays a critical role in suppressing mutations caused by the bypass of cis-syn cyclobutane pyrimidine dimers (CPD) that escape repair. There is evidence this is also the case for the oxidative lesion 7,8-dihydro-8-oxo-guanine (8-oxoG). Both of these lesions cause moderate to...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3669660/ https://ncbi.nlm.nih.gov/pubmed/23499771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2013.03.001 |
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