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Minimal Detection of Nuclear Mutations in XP-V and Normal Cells Treated with Oxidative Stress Inducing Agents
Elevated levels of reactive oxygen species (ROS) can be induced by exposure to various chemicals and radiation. One type of damage in DNA produced by ROS is modification of guanine to 7,8-dihydro-8-oxoguanine (8-oxoG). This particular alteration to the chemistry of the base can inhibit the replicati...
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| Veröffentlicht in: | J Biochem Mol Toxicol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4257877/ https://ncbi.nlm.nih.gov/pubmed/25165004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.21599 |
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