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Minimal Detection of Nuclear Mutations in XP-V and Normal Cells Treated with Oxidative Stress Inducing Agents

Elevated levels of reactive oxygen species (ROS) can be induced by exposure to various chemicals and radiation. One type of damage in DNA produced by ROS is modification of guanine to 7,8-dihydro-8-oxoguanine (8-oxoG). This particular alteration to the chemistry of the base can inhibit the replicati...

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Dades bibliogràfiques
Publicat a:J Biochem Mol Toxicol
Autors principals: Herman, Kimberly N., Toffton, Shannon, McCulloch, Scott D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257877/
https://ncbi.nlm.nih.gov/pubmed/25165004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.21599
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