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Detrimental Effects of UV-B Radiation in a Xeroderma Pigmentosum-Variant Cell Line

DNA polymerase η (pol η), of the Y-family, is well known for its in vitro DNA lesion bypass ability. The most well-characterized lesion bypassed by this polymerase is the cyclobutane pyrimidine dimer (CPD) caused by ultraviolet (UV) light. Historically, cellular and whole-animal models for this area...

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Autors principals: Herman, Kimberly N., Toffton, Shannon, McCulloch, Scott D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102177/
https://ncbi.nlm.nih.gov/pubmed/24549972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21857
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