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Minimal Detection of Nuclear Mutations in XP-V and Normal Cells Treated with Oxidative Stress Inducing Agents

Elevated levels of reactive oxygen species (ROS) can be induced by exposure to various chemicals and radiation. One type of damage in DNA produced by ROS is modification of guanine to 7,8-dihydro-8-oxoguanine (8-oxoG). This particular alteration to the chemistry of the base can inhibit the replicati...

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Detalles Bibliográficos
Publicado en:J Biochem Mol Toxicol
Autores principales: Herman, Kimberly N., Toffton, Shannon, McCulloch, Scott D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257877/
https://ncbi.nlm.nih.gov/pubmed/25165004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.21599
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