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Biochemical Analysis of DNA Polymerase η Fidelity in the Presence of Replication Protein A
DNA polymerase η (pol η) synthesizes across from damaged DNA templates in order to prevent deleterious consequences like replication fork collapse and double-strand breaks. This process, termed translesion synthesis (TLS), is an overall positive for the cell, as cells deficient in pol η display high...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019591/ https://ncbi.nlm.nih.gov/pubmed/24824831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097382 |
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