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PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells
The inhibitory receptor programmed cell death 1 (PD-1) plays a major role in functional exhaustion of T cells during chronic infections and cancer, and recent clinical data suggest that blockade of the PD-1 pathway is an effective immunotherapy in treating certain cancers. Thus, it is important to d...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Clinical Investigation
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668811/ https://ncbi.nlm.nih.gov/pubmed/23676462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67008 |
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