Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes: IMPLICATIONS FOR DISEASE SPREADING AND MOTOR NEURON PATHOLOGY IN AMYOTROPHIC LATERAL SCLEROSIS

Amyotrophic lateral sclerosis is the most common motor neuron disease and is still incurable. The mechanisms leading to the selective motor neuron vulnerability are still not known. The interplay between motor neurons and astrocytes is crucial in the outcome of the disease. We show that mutant coppe...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Basso, Manuela, Pozzi, Silvia, Tortarolo, Massimo, Fiordaliso, Fabio, Bisighini, Cinzia, Pasetto, Laura, Spaltro, Gabriella, Lidonnici, Dario, Gensano, Francesco, Battaglia, Elisa, Bendotti, Caterina, Bonetto, Valentina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Neurobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668729/
https://ncbi.nlm.nih.gov/pubmed/23592792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.425066
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