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New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models

Amyotrophic Lateral Sclerosis (ALS) is a heterogeneous disease in terms of progression rate and survival. This is probably one of the reasons for the failure of many clinical trials and the lack of effective therapies. Similar variability is also seen in SOD1(G93A) mouse models based on their geneti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Brain Pathol
Main Authors: Nardo, Giovanni, Trolese, Maria Chiara, Tortarolo, Massimo, Vallarola, Antonio, Freschi, Mattia, Pasetto, Laura, Bonetto, Valentina, Bendotti, Caterina
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029191/
https://ncbi.nlm.nih.gov/pubmed/26780365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12351
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