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New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models

Amyotrophic Lateral Sclerosis (ALS) is a heterogeneous disease in terms of progression rate and survival. This is probably one of the reasons for the failure of many clinical trials and the lack of effective therapies. Similar variability is also seen in SOD1(G93A) mouse models based on their geneti...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Nardo, Giovanni, Trolese, Maria Chiara, Tortarolo, Massimo, Vallarola, Antonio, Freschi, Mattia, Pasetto, Laura, Bonetto, Valentina, Bendotti, Caterina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029191/
https://ncbi.nlm.nih.gov/pubmed/26780365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12351
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