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Similar 150-kilobase DNA sequences are amplified in independently derived methotrexate-resistant Chinese hamster cells.

We have isolated overlapping recombinant cosmids that represent 150 kilobases of contiguous DNA sequence from the amplified dihydrofolate reductase domain of a methotrexate-resistant Chinese hamster ovary cell line (CHOC 400). This sequence includes the 25-kilobase dihydrofolate reductase gene and a...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Montoya-Zavala, M, Hamlin, J L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1985
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2985962/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.4.619-627.1985
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