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Recombinant Human Acid Sphingomyelinase as an Adjuvant to Sorafenib Treatment of Experimental Liver Cancer

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the third leading cause of cancer death worldwide. The only approved systemic treatment for unresectable HCC is the oral kinase inhibitor, sorafenib. Recombinant human acid sphingomyelinase (rhASM), which hydrolyz...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Savić, Radoslav, He, Xingxuan, Fiel, Isabel, Schuchman, Edward H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665770/
https://ncbi.nlm.nih.gov/pubmed/23724146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065620
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