The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

Acid sphingomyelinase (ASM; E.C. 3.1.4.12) is best known for its involvement in the lysosomal storage disorder Niemann-Pick disease (NPD). Through studies that began by investigating this rare disease, recent findings have uncovered the important role of this enzyme in the initiation of ceramide-med...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, Eric L., Schuchman, Edward H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Federation of American Societies for Experimental Biology 2008
Konular:
Reviews
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537423/
https://ncbi.nlm.nih.gov/pubmed/18567738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-108043
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