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Brain pathology in Niemann Pick disease type A: Insights from the acid sphingomyelinase knockout mice

Severe neurological involvement characterizes Niemann Pick disease (NPD) type A, an inherited disorder caused by loss of function mutations in the gene encoding acid sphingomyelinase (ASM). Mice lacking ASM (ASMko), which mimic NPD type A, have provided important insights into the aberrant brain phe...

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Detaylı Bibliyografya
Asıl Yazarlar: Ledesma, Maria Dolores, Prinetti, Alessandro, Sonnino, Sandro, Schuchman, Edward H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059095/
https://ncbi.nlm.nih.gov/pubmed/21214563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07034.x
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