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The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases
Acid sphingomyelinase (ASM; E.C. 3.1.4.12) is best known for its involvement in the lysosomal storage disorder Niemann-Pick disease (NPD). Through studies that began by investigating this rare disease, recent findings have uncovered the important role of this enzyme in the initiation of ceramide-med...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Federation of American Societies for Experimental Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2537423/ https://ncbi.nlm.nih.gov/pubmed/18567738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-108043 |
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