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PGC-1α Is a Central Negative Regulator of Vascular Senescence
OBJECTIVE: Cellular senescence influences organismal aging and increases predisposition to age-related diseases, in particular cardiovascular disease, a leading cause of death and disability worldwide. PGC-1α is a master regulator of mitochondrial biogenesis and function, oxidative stress and insuli...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663327/ https://ncbi.nlm.nih.gov/pubmed/23430617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301019 |
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