PGC-1α Serine 570 Phosphorylation and GCN5-mediated Acetylation by Angiotensin II Drive Catalase Down-regulation and Vascular Hypertrophy

Angiotensin II (Ang II) is a pleuripotential hormone that is important in the pathophysiology of multiple conditions including aging, cardiovascular and renal diseases, and insulin resistance. Reactive oxygen species (ROS) are important mediators of Ang II-induced signaling generally and have a well...

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Detalhes bibliográficos
Main Authors: Xiong, Shiqin, Salazar, Gloria, San Martin, Alejandra, Ahmad, Mushtaq, Patrushev, Nikolay, Hilenski, Lula, Nazarewicz, Rafal Robert, Ma, Minhui, Ushio-Fukai, Masuko, Alexander, R. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807304/
https://ncbi.nlm.nih.gov/pubmed/19940161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065235
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