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PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases
Cellular senescence and organismal aging predispose age-related chronic diseases such as neurodegenerative, metabolic and cardiovascular disorders. These diseases emerge coincidently from elevated oxidative/electrophilic stress, inflammation, mitochondrial dysfunction, DNA damage and telomere dysfun...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549794/ https://ncbi.nlm.nih.gov/pubmed/26299964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.047 |
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