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Multivariate methods and software for association mapping in dose‐response genome‐wide association studies

BACKGROUND: The large sample sizes, freedom of ethical restrictions and ease of repeated measurements make cytotoxicity assays of immortalized lymphoblastoid cell lines a powerful new in vitro method in pharmacogenomics research. However, previous studies may have over‐simplified the complex differe...

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Détails bibliographiques
Auteurs principaux: Brown, Chad C, Havener, Tammy M, Medina, Marisa Wong, Krauss, Ronald M, McLeod, Howard L, Motsinger‐Reif, Alison A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661384/
https://ncbi.nlm.nih.gov/pubmed/23234571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-5-21
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