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Genome-wide Association and Pharmacological Profiling of 29 Anticancer Agents Using Lymphoblastoid Cell Lines

AIMS: Association mapping with lymphoblastoid cell lines (LCLs) is a promising approach in pharmacogenomics research, and in the current study we utilize this model to perform association mapping for 29 chemotherapy drugs. MATERIALS AND METHODS: Currently, we use LCLs to perform genome-wide associat...

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Detalhes bibliográficos
Main Authors: Brown, Chad C., Havener, Tammy M., Medina, Marisa W., Jack, John R., Krauss, Ronald M., McLeod, Howard L., Motsinger-Reif, Alison A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055088/
https://ncbi.nlm.nih.gov/pubmed/24444404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.213
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