A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines reveals a clinically relevant association with MGMT

Recently, lymphoblastoid cell lines (LCLs) have emerged as an innovative model system for mapping gene variants that predict dose response to chemotherapy drugs. In the current study, this strategy was expanded to the in vitro genome-wide association approach, using 516 LCLs derived from a Caucasian...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Brown, Chad C., Havener, Tammy M., Medina, Marisa Wong, Auman, J. Todd, Mangravite, Lara M., Krauss, Ronald M., McLeod, Howard L., Motsinger-Reif, Alison A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691078/
https://ncbi.nlm.nih.gov/pubmed/23047291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283589c50
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