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Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines

Lymphoblastoid cell lines (LCLs) are a highly successful model for evaluating the genetic etiology of cancer drug response, but applications using this model have typically focused on single drugs. Combination therapy is quite common in modern chemotherapy treatment since drugs often work synergisti...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Roell, Kyle R., Havener, Tammy M., Reif, David M., Jack, John, McLeod, Howard L., Wiltshire, Tim, Motsinger-Reif, Alison A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804467/
https://ncbi.nlm.nih.gov/pubmed/31681399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00829
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