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Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines

Lymphoblastoid cell lines (LCLs) are a highly successful model for evaluating the genetic etiology of cancer drug response, but applications using this model have typically focused on single drugs. Combination therapy is quite common in modern chemotherapy treatment since drugs often work synergisti...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Roell, Kyle R., Havener, Tammy M., Reif, David M., Jack, John, McLeod, Howard L., Wiltshire, Tim, Motsinger-Reif, Alison A.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804467/
https://ncbi.nlm.nih.gov/pubmed/31681399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00829
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