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Race and smoking status associated with paclitaxel drug response in patient-derived lymphoblastoid cell lines

The use of ex vivo model systems to provide a level of forecasting for in vivo characteristics remains an important need for cancer therapeutics. The use of lymphoblastoid cell lines (LCLs) is an attractive approach for pharmacogenomics and toxicogenomics, due to their scalability, efficiency and co...

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Dettagli Bibliografici
Pubblicato in:Pharmacogenet Genomics
Autori principali: Akhtari, Farida S., Havener, Tammy M., Hertz, Daniel L, Ash, Jeremy, Larson, Alexandra, Carey, Lisa A., McLeod, Howard L., Motsinger-Reif, Alison A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320509/
https://ncbi.nlm.nih.gov/pubmed/32941389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000419
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