Evaluating the role of admixture in cancer therapy via in vitro drug response and multivariate genome-wide associations

AIM: We investigate the role of ethnicity and admixture in drug response across a broad group of chemotherapeutic drugs. Also, we generate hypotheses on the genetic variants driving differential drug response through multivariate genome-wide association studies. METHODS: Immortalized lymphoblastoid...

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Vydáno v:Pharmacogenomics
Hlavní autoři: Jack, John, Havener, Tammy M, McLeod, Howard L, Motsinger-Reif, Alison A, Foster, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810848/
https://ncbi.nlm.nih.gov/pubmed/26314407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.15.85
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