Ex-Vivo Modeling for Heritability Assessment and Genetic Mapping in Pharmacogenomics

The investigation of genetic factors that determine differential drug response is a key goal of pharmacogenomics (PGX), and relies on the often-untested assumption that differential response is heritable. While limitations in traditional study design often prohibit heritability (h(2)) estimates in P...

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Udgivet i:Proc Am Stat Assoc
Main Authors: Motsinger-Reif, Alison, Brown, Chad, Havener, Tammy, Hardison, Nicholas, Peters, Eric, Beam, Andrew, Everrit, Lorri, McLeod, Howard
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322852/
https://ncbi.nlm.nih.gov/pubmed/30627054
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