Pharmacogenomic characterization of US FDA-approved cytotoxic drugs

AIMS: Individualization of cancer chemotherapy based on the patient’s genetic makeup holds promise for reducing side effects and improving efficacy. However, the relative contribution of genetics to drug response is unknown. MATERIALS & METHODS: In this study, we investigated the cytotoxic effec...

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Autori principali: Peters, Eric J, Motsinger-Reif, Alison, Havener, Tammy M, Everitt, Lorraine, Hardison, Nicholas E, Watson, Venita G, Wagner, Michael, Richards, Kristy L, Province, Mike A, McLeod, Howard L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399590/
https://ncbi.nlm.nih.gov/pubmed/22008047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.11.92
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