Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics

BACKGROUND: The goal of this study was to perform candidate gene association with cytotoxicity of chemotherapeutics in cell line models through resequencing and discovery of rare and low frequency variants along with common variations. Here, an association study of cytotoxicity response to 30 FDA ap...

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Autores principales: Hariani, Gunjan D, Lam, Ernest J, Havener, Tammy, Kwok, Pui-Yan, McLeod, Howard L, Wagner, Michael J, Motsinger-Reif, Alison A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068968/
https://ncbi.nlm.nih.gov/pubmed/24924344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-360
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