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Genomic Profiling in CEPH cell lines Distinguishes between the Camptothecins and Indenoisoquinolines
We have attempted to use a familial genetics strategy to study mechanisms of Topoisomerase 1 (Top1) inhibition. Investigations have steadily been chipping away at the pathways involved in cellular response following Top1 inhibition for more than 20 years. Our system-wide approach, which phenotypes a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191307/ https://ncbi.nlm.nih.gov/pubmed/21750217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0872 |
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