Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease

The low frequency of naturally occurring regulatory T cells (nTregs) in peripheral blood and the suboptimal protocols available for their ex vivo expansion limit the development of clinical trials based on the adoptive transfer of these cells. We have, therefore, generated a simplified, robust and c...

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Bibliographische Detailangaben
Hauptverfasser: Chakraborty, Rikhia, Mahendravada, Aruna, Perna, Serena K., Rooney, Cliona M., Heslop, Helen E., Vera, Juan F., Savoldo, Barbara, Dotti, Gianpietro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2013
Schlagworte:
Original Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659983/
https://ncbi.nlm.nih.gov/pubmed/23242592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.076430
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