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Interleukin-7 mediates selective expansion of tumor-redirected cytotoxic T lymphocytes without enhancement of regulatory T-cell inhibition

PURPOSE: The antitumor activity of chimeric antigen receptor (CAR)-redirected cytotoxic T lymphocytes (CTLs) should be enhanced if it were possible to increase their proliferation and function after adoptive transfer without concomitantly increasing the proliferation and function of regulatory T cel...

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Detalhes bibliográficos
Main Authors: Perna, Serena K., Pagliara, Daria, Mahendravada, Aruna, Liu, Hao, Brenner, Malcolm, Savoldo, Barbara, Dotti, Gianpietro
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113428/
https://ncbi.nlm.nih.gov/pubmed/24097874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1016
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