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Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease

The low frequency of naturally occurring regulatory T cells (nTregs) in peripheral blood and the suboptimal protocols available for their ex vivo expansion limit the development of clinical trials based on the adoptive transfer of these cells. We have, therefore, generated a simplified, robust and c...

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Autori principali: Chakraborty, Rikhia, Mahendravada, Aruna, Perna, Serena K., Rooney, Cliona M., Heslop, Helen E., Vera, Juan F., Savoldo, Barbara, Dotti, Gianpietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659983/
https://ncbi.nlm.nih.gov/pubmed/23242592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.076430
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