Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease

The low frequency of naturally occurring regulatory T cells (nTregs) in peripheral blood and the suboptimal protocols available for their ex vivo expansion limit the development of clinical trials based on the adoptive transfer of these cells. We have, therefore, generated a simplified, robust and c...

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Hlavní autoři: Chakraborty, Rikhia, Mahendravada, Aruna, Perna, Serena K., Rooney, Cliona M., Heslop, Helen E., Vera, Juan F., Savoldo, Barbara, Dotti, Gianpietro
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2013
Témata:
Original Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659983/
https://ncbi.nlm.nih.gov/pubmed/23242592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.076430
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