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Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
The mechanisms by which the p53 tumor suppressor acts remain incompletely understood. To gain new insights into p53 biology, we used high-throughput sequencing to analyze global p53 transcriptional networks in primary mouse embryo fibroblasts in response to DNA damage. Chromatin immunoprecipitation...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656320/ https://ncbi.nlm.nih.gov/pubmed/23651856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212282.112 |
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