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Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function

The p53 tumor suppressor plays a key role in maintaining cellular integrity. In response to diverse stress signals, p53 can trigger apoptosis to eliminate damaged cells or cell-cycle arrest to enable cells to cope with stress and survive. However, the transcriptional networks underlying p53 pro-surv...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Jiang, Dadi, LaGory, Edward L., Brož, Daniela Kenzelmann, Bieging, Kathryn T., Brady, Colleen A., Link, Nichole, Abrams, John M., Giaccia, Amato J., Attardi, Laura D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365998/
https://ncbi.nlm.nih.gov/pubmed/25704813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.043
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