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Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
Aggregation of misfolded proteins and the associated loss of neurons are considered as a hallmark of numerous neurodegenerative diseases. Optineurin is present in protein inclusions observed in various neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), Huntington’s disease, Al...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654196/ https://ncbi.nlm.nih.gov/pubmed/23178947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.114926 |
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