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Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
Aggregation of misfolded proteins and the associated loss of neurons are considered as a hallmark of numerous neurodegenerative diseases. Optineurin is present in protein inclusions observed in various neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), Huntington’s disease, Al...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654196/ https://ncbi.nlm.nih.gov/pubmed/23178947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.114926 |
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