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Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

Aggregation of misfolded proteins and the associated loss of neurons are considered as a hallmark of numerous neurodegenerative diseases. Optineurin is present in protein inclusions observed in various neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), Huntington’s disease, Al...

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Detaylı Bibliyografya
Asıl Yazarlar: Korac, Jelena, Schaeffer, Veronique, Kovacevic, Igor, Clement, Albrecht M., Jungblut, Benno, Behl, Christian, Terzic, Janos, Dikic, Ivan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654196/
https://ncbi.nlm.nih.gov/pubmed/23178947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.114926
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