Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange.
The neutralizing monoclonal antibody Y13-259 severely hampers the nucleotide exchange reaction between p21-bound and exogenous guanine nucleotides but does not interfere with the association of GDP to p21. These results suggest that the nucleotide exchange reaction is critical for p21 function. Inte...
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| Vydáno v: | Mol Cell Biol |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1987
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.1999-2002.1987 |
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